Publications and evidence

Work that stands up to scrutiny.

Prima Nexus is dedicated to helping scientists and researchers with reliable, quality-controlled products and services. The programs we coordinate have supported more than 100 papers published in peer-reviewed SCI journals. A selection is listed below, each linked to its published record.

100+

Papers supported in SCI journals

40+

Institutions supported

14,000+

Tests delivered

Core research domains

Publication library

Peer-reviewed work, by platform.

Grouped by the technology platform behind each study, spanning oncology, immunology, infectious and tropical disease, metabolic and neuroscience research.

Platform

Multiplex Immunoassay

Cytokine Expression Profile of Dengue Patients at Different Phases of IllnessPubMed ↗

Circulating cytokines and small molecules follow distinct expression patterns in acute myeloid leukaemiaPubMed ↗

Autologous serum supplement favours in vitro regenerative paracrine factors synthesisPubMed ↗

Palm olein and olive oil cause a higher increase in postprandial lipemia compared with lard but had no effect on plasma glucose, insulin and adipocytokinesPubMed ↗

Assessment of cytotoxicity potency of paclitaxel in combination with Clinacanthus nutans extracts on human MDA-MB-231 breast cancer cellsScholar ↗

Anti-inflammatory evaluation of Scurrula ferruginea (Jack) Danser parasitizing on Tecoma stans (L.) HBK in LPS/IFN-γ-induced RAW 264.7 macrophagesScienceDirect ↗

In Vitro and In Vivo Anti-Inflammatory Activity of 17-O-Acetylacuminolide through the Inhibition of Cytokines, NF-kB Translocation and IKKβ ActivityPLOS ↗

Platform

QuantiGene Plex

Expression and mutational analysis of GATA3 in Malaysian breast carcinomasPubMed ↗

Novel fish oil-based bigel system for controlled drug delivery and its influence on immunomodulatory activity of imiquimod against skin cancerSpringer ↗

Labisia pumila regulates bone-related genes expressions in postmenopausal osteoporosis modelPubMed ↗

Eurycoma longifolia upregulates osteoprotegerin gene expression in androgen-deficient osteoporosis rat modelBMC ↗

Palm tocotrienols decrease levels of pro-angiogenic markers in human umbilical vein endothelial cells (HUVEC) and murine mammary cancer cellsPMC ↗

Effects of annatto-derived tocotrienol supplementation on osteoporosis induced by testosterone deficiency in ratsPubMed ↗

Platform

Flow Cytometry

In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cellsPubMed ↗

L1CAM, CA9, KLK6, HPN, and ALDH1A1 as Potential Serum Markers in Primary and Metastatic Colorectal Cancer ScreeningMDPI ↗

Rosiglitazone diminishes the high-glucose-induced modulation of 5-fluorouracil cytotoxicity in colorectal cancer cellsPubMed ↗

Rosiglitazone enhances the apoptotic effect of 5-fluorouracil in colorectal cancer cells with high-glucose-induced glutathionePubMed ↗

In vitro Anti-colorectal Cancer Potential of the Medicinal Mushroom Ganoderma neo-japonicum Imazeki in Hyperglycemic Condition: Impact on Oxidative Stress, Cell Cycle and ApoptosisPubMed ↗

Establishing SW1353 Chondrocytes as a Cellular Model of ChondrolysisMDPI ↗

Antimutagenic, Cytoprotective and Antioxidant Properties of Ficus deltoidea Aqueous Extract In VitroMDPI ↗

Herbal formulation C168 attenuates proliferation and induces apoptosis in HCT 116 human colorectal carcinoma cells: Role of oxidative stress and DNA damageScholar ↗

Platform

LC-MS

In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cellsPubMed ↗

Herbal formulation C168 attenuates proliferation and induces apoptosis in HCT 116 human colorectal carcinoma cells: Role of oxidative stress and DNA damageScholar ↗

Acute toxicity evaluation of homeopathic preparation of Gymnema sylvestre and analysis of its chemical constituentsPDF ↗

Platform

Protein Array

Induction of Apoptotic Mechanism by Streblus asper Root Extract on Cervical Cancer Using in Vitro and in Vivo ModelsPDF ↗

Platform

Animal-Related Work

In vivo study of homoeopathic preparation of Gymnema sylvestre mother tincture, 30C and 200C on streptozotocin-induced diabetic ratsIJRH ↗

Serum Metabolomics Profiling of Commercially Mixed Functional Foods, Effects in Beta-Amyloid Induced Rats Measured Using 1H NMR SpectroscopyPubMed ↗

Neuroprotection of Tropical Fruit Juice Mixture via the Reduction of iNOS Expression and CRH Level in β-Amyloid-Induced Rats Model of Alzheimer's DiseaseEBSCO ↗

Each title links to the publisher, PubMed, or repository record. This selection is illustrative of work supported across our platforms; a fuller list is available on request.

They run trials and experiments in a meticulous way for each kit, with results generated quickly and clearly. It eased up my time for data analysis.

Dr. Lelia Tay · PPUKM

Great service, quick delivery, the order was constantly updated and I was well informed. Data and results were consistent.

Dr. Priyadarshni Bindal · Universiti Malaya

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